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After inducing Keap1 deletion in MuSCs from adult mice by TMX injection, we monitored the number of YFP + MuSCs by FACS at different time points after the last TMX injection in both male and female mice

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This approach has been described as a “senolytic” strategy — selectively eliminating senescent cells while sparing non-senescent cells that do not depend on the FOXO4-p53 interaction for survival

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